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Not goo, but clearly made of slime,

You try to play, and play me, I'm

Not fair and all goes up as I

Will drop, for you know I can't fly,

And so all goes hell and high, and voices clamour,

Crying yammer.

'Slime and clamour, you must be perfectly uncomfortable.'
'I...don't know what you mean.'
'I can see you squirming.'

Riddle Answer A Ball

Riddle Explanation
not goo, but clearly made of slime - a slime ball

you try to play, and play me, I'm not fair - to play ball literally, or figuratively to fairly participate.

and all goes up as I - to go balls-up.

will drop, for you know I can't fly, and so all goes hell and high - to drop the ball.

and voices clamour, crying yammer - to ball or bawl, or to cry vigorously.